Los Angeles Chargers running back Melvin Gordon was ruled inactive for Sunday's game against the Tennessee Titans in London.
Gordon was limited in practice on Friday, but the Chargers did not place an injury designation on him. Los Angeles coach Anthony Lynn at first said Gordon was affected by dehydration from the long flight to England.
Lynn also reasoned that Gordon did not practice much Friday because he is affected by his knees and ankles practicing three straight days.
Austin Ekeler is expected to see a bigger workload in the absence of Gordon. Rookie Justin Jackson could also be used more.
Gordon, a four-year player out of Wisconsin, leads the AFC with 466 rushing yards and has scored all six of the Chargers' touchdowns on the ground. Three of those scores came last week against Cleveland. He is second on the team with 30 receptions for another 279 yards.
The 25-year-old Gordon played a full 16-game season for the first time last year, finishing with 342 touches in 2017, fourth in the NFL. Since the start of the 2016 season, Gordon's 33 scores are only surpassed by Los Angeles Rams star Todd Gurley (36).
The other inactive Chargers are kicker Caleb Sturgis, linebacker Kyzir White, center Cole Toner, tackle Trent Scott, guard Forrest Lamp and defensive end Joey Bosa.